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Procedures

WWARN is continually updating a library of standardised procedures that offer guidance in the execution of various activities in the fields of clinical, in vitro, pharmacology, data collection and molecular analysis for antimalarial drug resistance researchers. Please read our tools and resources usage guidance.

For resources that relate to other infectious and emerging diseases, visit iddo.org.

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QA10
Organising trial initiation meetings
A process for when the trial site arranges the initiation meeting/visit for a trial
Version: 2.0 Author: WWARN
AD02
Set up and maintenance of the Investigator Site File
A process for sites for generating important documents and a systematic filing system
Version: 2.0 Author: WWARN
AD04
General preparation for clinical trial conduct
A process for ensuring that stock, equipment, documentation, staff and venue are adequately prepared for a new clinical trial
Version: 2.0 Author: WWARN
AD12
Archiving of clinical trial Essential Documents
A process for archiving Essential Documents generated during a malaria clinical trial
Version: 2.0 Author: WWARN
INV11
Piperaquine Survival Assays (PSA) to evaluate the in-vitro and ex-vivo susceptibility of Plasmodium falciparum to piperaquine
This procedure describes two assays to evaluate the susceptibility of Plasmodium falciparum to piperaquine.
Version: V1.0 Author: Benoit Witkowski & Didier Ménard, Institut Pasteur du Cambodge
CLI19
Obare Method Calculator
A tool to calculate the mean parasite density and assessing whether two blood samples are concordant
Version: v1.0 Author: Obare
EXT11
Guidelines for the Cryopreservation of field isolates
The purpose of this document is to standardize the methodology for cryopreservation of malaria parasites using glycerolyte
Version: 1.0 Author: Dr. Kesinee Chotivanich
INV10
Ring-stage Survival Assays (RSA) to Evaluate the In-Vitro and Ex-Vivo Susceptibility of Plasmodium Falciparum to Artemisinins
Evaluting Plasmodium falciparum susceptibility to artemisinins in laboratory strains and fresh isolates
Version: v1.2 Author: Institut Pasteur du Cambodge & National Institute of Allergy and Infectious Diseases/NIH
EXT10
Microscopy for the detection, identification and quantification of malaria parasites on stained thick and thin blood films in research settings
This manual was developed to guide a move towards common standards for undertaking and reporting research microscopy for malaria parasite detection, identification and quantification.
Version: 1.0 Author: Research Malaria Microscopy Standards Working Group
CL22
Collection of samples for artemisinin pharmacology analysis
These guidelines aim to standardize the sample collection procedure during clinical studies of artemisinin antimalarial drugs
Version: 2.0 Author: Chris Lourens

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