Molecular Surveyor dhfr-dhps - Methodology
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Africa
- Data provided by Inbarani Naidoo and Cally Roper at the London School of Hygiene and Tropical Medicine
- Literature searches used Pubmed, African Journal Online and Bioline
- Search terms were "malaria" and "dhfr" or "dhps" or "540" or "437" or "436" or "581" or "51" or "59" or "108" or "164"
- Studies had to include analysis of dhfr or dhps genes in P falciparum isolates sampled from infected people living in a clearly identified geographical site(s) in Africa
- Abstracts and full text of suitable studies were reviewed and prevalence of wild-type and mutant sequences was recorded
- Searches conducted from October 2005 to January 2011
Asia
- Data provided by Mallika Imwong and team at the Faculty of Tropical Medicine, Mahidol University
- Literature searches used Pubmed
- Searches terms were "falciparum" and "Asia" and "dhfr" or "dhps"
- Studies had to include analysis of dhfr or dhps genes in P falciparum isolates sampled from infected people living in clearly identified geographical site(s) in Asia
- Abstracts and full text of suitable studies were reviewed and prevalence of wild-type and mutant sequences was recorded in a total of 33 studies
- Searches conducted in March 2010
Latin America
- Data provided by Vladimir Corredor, Faculty of Medicine, Universidad Nacional de Colombia
- Literature searches used Pubmed, SciELO, Bioonline and Biblioteca Virtual de Salud
- Search terms were "malaria drug resistance" or "dhfr falciparum" or "dhps falciparum" and "South America" or "[name of each country comprising South America]"
- Abstracts and full text of suitable studies were reviewed and prevalence of wild-type and mutant sequences was recorded in a total of 24 studies
- Search conducted in 2009 and updated in Feb 2011
Locations and years
- Study locations and years are based on information presented in publications or provided by authors
- ‘Estimated location’ is used when specific site names could not be found or the publication merged samples from multiple sites
- Sample collection years that were estimated by the study authors are indicated as such
- Studies for which a sample collection time could not be found were attributed an estimated sample collection time of 3 years prior to the year of publication.