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On-site monitoring
Procedure
For when an investigator/institution takes responsibility for on-site monitoring of a clinical trial
Version: 2.0
Author: WWARN
Safety assessment and reporting
Procedure
A process for the identification, management, assessment, and reporting of adverse events/adverse drug reactions
Version: v1.0
Author: WWARN
Ring-stage Survival Assays (RSA) to Evaluate the In-Vitro and Ex-Vivo Susceptibility of Plasmodium Falciparum to Artemisinins
Procedure
Evaluting Plasmodium falciparum susceptibility to artemisinins in laboratory strains and fresh isolates
Version: v1.2
Author: Institut Pasteur du Cambodge & National Institute of Allergy and Infectious Diseases/NIH
DNA extraction by Chelex
Procedure
Extracting Plasmodium spp. DNA from dried blood spots by Chelex 100
Version: 1.0
Author: Mekong Molecular Surveillance Network
Sample Preservation
Procedure
Collecting and preserving DNA, RNA and parasite isolates from infected blood samples
Version: v1.5
Author: WWARN
Microscopy for the detection, identification and quantification of malaria parasites on stained thick and thin blood films in research settings
Procedure
This manual was developed to guide a move towards common standards for undertaking and reporting research microscopy for malaria parasite detection, identification and quantification.
Version: 1.0
Author: Research Malaria Microscopy Standards Working Group
Methods and techniques for assessing exposure to antimalarial drugs in clinical field studies
Publications
Estimation of Plasmodium falciparum drug susceptibility by the SYBR® Green assay
Procedure
Drug susceptibility assay measuring SYBR®Green I fluorescence in laboratory strains and field isolates
Version: 1.0
Author: WWARN
PCR and sequencing for genotyping of candidate Plasmodium falciparum artemisinin resistance SNPs in the Kelch 13 gene
Procedure
Genotyping of SNPs in the Kelch 13 gene (PF3D7_1343700), associated with artemisinin resistance
Version: 1.0
Author: D. Menard & F. Ariey Institut Pasteur
Agarose Gel Electrophoresis of msp1, msp2 and glurp
Procedure
Separating and visualising amplified PCR products of msp1, msp2 and glurp
Version: 1.0
Author: Mekong Molecular Surveillance Network