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On-site monitoring
Procedure
For when an investigator/institution takes responsibility for on-site monitoring of a clinical trial
Version: 2.0
Author: WWARN
Safety assessment and reporting
Procedure
A process for the identification, management, assessment, and reporting of adverse events/adverse drug reactions
Version: v1.0
Author: WWARN
Microscopy for the detection, identification and quantification of malaria parasites on stained thick and thin blood films in research settings
Procedure
This manual was developed to guide a move towards common standards for undertaking and reporting research microscopy for malaria parasite detection, identification and quantification.
Version: 1.0
Author: Research Malaria Microscopy Standards Working Group
Estimation of Plasmodium falciparum drug susceptibility by the SYBR® Green assay
Procedure
Drug susceptibility assay measuring SYBR®Green I fluorescence in laboratory strains and field isolates
Version: 1.0
Author: WWARN
PCR and sequencing for genotyping of candidate Plasmodium falciparum artemisinin resistance SNPs in the Kelch 13 gene
Procedure
Genotyping of SNPs in the Kelch 13 gene (PF3D7_1343700), associated with artemisinin resistance
Version: 1.0
Author: D. Menard & F. Ariey Institut Pasteur
Agarose Gel Electrophoresis of msp1, msp2 and glurp
Procedure
Separating and visualising amplified PCR products of msp1, msp2 and glurp
Version: 1.0
Author: Mekong Molecular Surveillance Network
Estimation of Plasmodium falciparum drug susceptibility ex vivo by HRP2 ELISA
Procedure
Drug susceptibility assay measuring histidine-rich protein production by ELISA in fresh isolates
Version: v1.0
Author: WWARN
Manual size estimation of msp1, msp2 and glurp PCR products on gel
Procedure
Manually determining the size of Plasmodium falciparum polymorphic markers to distinguish recrudesent from reinfecting infections in clinical trials
Version: 1.0
Author: Mekong Molecular Surveillance Network
Preparing malaria blood smears
Procedure
Preparing thick and thin blood smears with Giemsa staining
Version: 2.0
Author: WWARN