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On-site monitoring
Procedure
For when an investigator/institution takes responsibility for on-site monitoring of a clinical trial
Version: 2.0
Author: WWARN
Safety assessment and reporting
Procedure
A process for the identification, management, assessment, and reporting of adverse events/adverse drug reactions
Version: v1.0
Author: WWARN
Preparing malaria blood smears
Procedure
Preparing thick and thin blood smears with Giemsa staining
Version: 2.0
Author: WWARN
Manual size estimation of msp1, msp2 and glurp PCR products on gel
Procedure
Manually determining the size of Plasmodium falciparum polymorphic markers to distinguish recrudesent from reinfecting infections in clinical trials
Version: 1.0
Author: Mekong Molecular Surveillance Network
DNA Extraction: Preparing Rapid Diagnostic Tests
Procedure
Storing and processing malaria Rapid Diagnostic Tests (RDTs) for DNA extraction
Version: v1.1
Author: WWARN
Estimation of Plasmodium falciparum drug susceptibility by the 3H-hypoxanthine uptake inhibition assay
Procedure
Drug susceptibility assay measuring radioactive hypoxanthine uptake in laboratory strains and fresh isolates.
Version: v1.0
Author: WWARN
glurp PCR
Procedure
PCR amplification of the polymorphic marker glurp to distinguish recrudescences from reinfections
Version: 1.0
Author: Mekong Molecular Surveillance Network
Culture of Plasmodium falciparum blood stages
Procedure
Methods for short- and long term culture of Plasmodium falciparum laboratory strains and fresh isolates
Version: v1.0
Author: WWARN
Preparation of drug plates for susceptibility assays
Procedure
Preparation of drug dilutions in dry or fresh plates for drug susceptibility assays
Version: v1.2
Author: WWARN
msp2 PCR
Procedure
PCR amplification of the polymorphic marker msp2 to distinguish recrudescences from reinfections
Version: 1.0
Author: Mekong Molecular Surveillance Network