Modules

Timely information is the key to defeating antimalarial resistance. WWARN will be a central repository of standardised data capable of providing early warning of emerging drug resistance.

The scientific work of WWARN is delivered through four modules, reflecting complementary aspects of antimalarial drug resistance. The WWARN database collates and analyses information from these modules:

- treatment outcomes and measures from clinical trials of drug efficacy;

- pharmacological profiles of antimalarial drugs across key target populations;

- in vitro assessment of drug susceptibility of parasite isolates;

- molecular markers of parasite resistance.

Integrated outputs from the database should provide early warning of emerging drug resistance, optimise drug selection and dosing, give a better understanding of the mechanisms of parasite resistance, and acclerate the identification, validation and application of artemisinin resistance markers.